Physiologically Based Pharmacokinetic (PBPK) modelling tools correlate environmental contamination threats with effects on the human health in order to make complex assessments of sustainable living achievement. PBPK models are a way to mathematically transcribe the anatomical, physiological, physical, and chemical descriptions of the occurrences involved in the complex processes of absorption, distribution, metabolism and excretion of synthetic or natural chemical substances in humans and other animal species. This mathematical technique is conventionally used in pharmaceutical research drug development and health risk assessment. The obtained models are used for managing disparate data from experiments, abstracting and combining them. By using existing information on the anatomical and physiological structure of the body, (and to a certain extent, on biochemistry) the models give access to internal body concentrations of chemicals or their metabolites. PBPK models are used to show the effects from exposure to a substance in those cases linear dose-response models cannot be used, due to variations in absorption, distribution, metabolism etc. between individuals.